Sublingual immunotherapy in allergic rhinitis

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Sublingual immunotherapy in allergic rhinitis

Current treatment options for allergic rhinitis (AR) include allergen avoidance and environmental control, pharmacotherapy, nasal surgery and immunotherapy. Among these, immunotherapy is the only therapeutic option that modifies fundamental immunologic mechanism by inducing desensitization. Specific allergen immunotherapy has been used for 1 century since 1911 and subcutaneous immunotherapy (SC...

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Sublingual Immunotherapy in Children with Allergic Rhinitis

The prevalence of allergic disease has been increasing over time and now represents a global health problem. For example, allergic disease in the UK affects up to 40% of children with allergic rhinitis accounting for a significant component of the allergic burden. There is also specific evidence for increasing prevalence of allergic rhinitis in the UK paediatric population, particularly among y...

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Sublingual immunotherapy for allergic rhinitis and conjunctivitis.

Sublingual immunotherapy (SLIT) for allergic respiratory diseases was first described in 1986 and immediately appeared as a viable alternative to the traditional subcutaneous route. Since then, more than 60 randomized controlled trials have been published, almost all with very favorable results. The average improvement over placebo in symptom score and medication use was always greater than 20%...

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Sublingual Immunotherapy in Allergic Rhinitis: Efficacy, Safety, Adherence and Guidelines

Allergic rhinitis (AR) is a globally increasing health problem affecting the quality of life. Specific immunotherapy is an available causal treatment changing the basic allergic mechanisms of the disease. Over one hundred years, subcutaneous immunotherapy (SCIT) was developed and proved its efficacy but many adverse effects were recorded including anaphylaxis. In 1986, sublingual immunotherapy ...

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Aim of the study was to evaluate the clinical efficacy of sublingual-oral immunotherapy in allergic rhinitis induced by various allergens and to demonstrate its effects using objective methods such as skin prick tests and specific IgE analysis. The first 100 patients diagnosed with allergic rhinitis and treated with sublingual-oral immunotherapy took part in the study and were followed for 2 ye...

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ژورنال

عنوان ژورنال: Asia Pacific Allergy

سال: 2011

ISSN: 2233-8276,2233-8268

DOI: 10.5415/apallergy.2011.1.3.123